Brian Shuch, MD, director of the UCLA Kidney Cancer Program, discusses considerations for partial or radical nephrectomy. Chronic kidney disease can lead to a loss of kidney function, which can be life-altering without renal replacement with dialysis or a kidney transplant. Dr Shuch emphasizes that urologists play a crucial role in kidney removal and managing future dysfunction. He also discusses the risks and benefits of partial and radical nephrectomy, stating that the decision should be individualized based on the patient’s kidney function, tumor factors, and patient factors.