In a presentation at the 2024 International Pathology Day virtual conference, Dr Justin Loke, CRUK/AACR Transatlantic Fellow, University of Birmingham, UK and Dana-Farber Cancer Institute, USA, explains how infection remains a major cause of sickness and death for patients with acute myeloid leukaemia (AML). He highlights ongoing innovative UK clinical trials aimed at reducing these infection risks, and discusses future strategies to further improve supportive care for vulnerable AML patients