At the 2022 European Society for Medical Oncology annual meeting, Charles Swanton, BSc, PhD, FRCP, The Francis Crick Institute, London, UK, presented research findings demonstrating how exposure to particulate matter (PM2.5) in the air may cause lung cancer among individuals without a history of smoking. In 2017, approximately 265,000 lung cancer deaths were attributed to air pollution, which is second only to tobacco smoking.