Muneeb Shah MD, and Luke Maxfield, MD, break down the essentials of skin cancer, explaining the causes, symptoms, and treatments of basal cell carcinoma, squamous cell carcinoma, and melanoma. They highlight the role of UV radiation, the “ugly duckling” sign, and the ABCDE rule in early detection. Advanced topics like Mohs micrographic surgery, radiation therapy, immunotherapy, and topical treatments are discussed. Emphasizing early detection and proactive care, they share insights for patients, families, and those diagnosed with skin cancer. The discussion also includes rarer cancers like Merkel cell carcinoma, encouraging vigilance and timely consultation with dermatologists.