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Part 3 - Case Discussion & Wrap-up Daniel A. Pollyea, MD, MS, presents the case of patient “A.B.” to fellow faculty members Brian A. Jonas, MD, PhD, FACP, and Gabriel N. Mannis, MD. The virtual roundtable panel discusses unique features of the case and explores hypothetical variations of the...
Megan Ryan shares her story from the point of learning about her diagnosis of CVID, finding information and support in the form of the Immune Deficiency Foundation (IDF), and attempting to understand enough about the condition to become actively involved in discussions and decisions regarding her treatment.
Don't let your "game stop" this Valentine's Day! From David, Mike, Elvis, and your cupids at: The Doctor's Channel, BESTMSLs, and MDea
We've known for centuries that alcohol consumed in excess can be deadly, but what's the truth about the effects of a daily glass of wine? The answer is nuanced, as may become apparent during the course of Dr. Hochman's interview with primary care doctor and alcohol researcher, Ken Mukamal, MD, MPH, of Beth...
[case_image][/case_image] [case_image_citation] Williams DB, Endicott T, Kaplan M, Douglas M.Consultant 2019;59(5):152-153. [/case_image_citation] [signs_symptoms]A 49-year-old man was referred to the ophthalmology clinic by his primary care physician, presenting with bilateral eyelid erythema that...
Part 1 - Case Presentation Brian A. Jonas, MD, PhD, FACP, presents the case of patient “J.S.” to fellow faculty members Daniel A. Pollyea, MD, MS, and Gabriel N. Mannis, MD. The virtual roundtable panel discusses unique features of the case and explores hypothetical variations of the circumstances, as...
Part 2 - Case Discussion Brian A. Jonas, MD, PhD, FACP, presents the case of patient “J.S.” to fellow faculty members Daniel A. Pollyea, MD, MS, and Gabriel N. Mannis, MD. The virtual roundtable panel discusses unique features of the case and explores hypothetical variations of the circumstances, as...
Part 3 - Case Discussion & Wrap-up Brian A. Jonas, MD, PhD, FACP, presents the case of patient “J.S.” to fellow faculty members Daniel A. Pollyea, MD, MS, and Gabriel N. Mannis, MD. The virtual roundtable panel discusses unique features of the case and explores hypothetical variations of the...

When Actin is Not Actin' Like it Should: A New Category of Distinct Primary Immunodeficiency Disorders

A New Category of Distinct Primary Immunodeficiency Disorders

In this review, the authors discuss “actinopathies” in terms of the clinical aspects and cellular mechanisms, with a focus on the effect of these mutations on neutrophil function. Several primary immunodeficiencies have been identified in the last 10 years, of which many are caused by mutations in genes...
Steven Quay, MD, PhD, physician-scientist and CEO of Atossa Therapeutics, discusses ongoing clinical trials of two treatments for patients infected with SARS-CoV-2 and how certain therapeutics will continue to play an important role in fighting the virus that causes COVID-19, even as vaccines become widely...