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First ‘Personalized’ Melanoma Skin Cancer Vaccine Trial Under Way in UK | BBC News
Melanoma Content Hub
A groundbreaking trial in the UK is testing the world’s first “personalized” mRNA vaccine against the deadliest form of skin cancer, melanoma. This innovative vaccine is tailored to…
5 Warning Signs of Melanoma | Melanoma & Skin Cancer Awareness Month – Dr. Rajdeep Mysore
Melanoma Content Hub
Rajdeep Mysore, MD discusses melanoma, the most dangerous type of skin cancer. Originating from melanocytes, the color-producing cells in the skin, melanomas often appear as black or brown…
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Chemo After PD-1 Inhibitor Blockade for Metastatic Melanoma Yields a Durable Response
Melanoma Content Hub
After prior case studies showed promising results with PD-1 inhibition followed by chemotherapy, a group of doctors, led by Georgia Sofia Karachaliou, MD, MSc, of the Department of Medicine…
SLNB in Melanoma: Recent Research Context
Melanoma Content Hub
Published final results of the DeCOG-SLT trial add evidence that patients who have a positive sentinel lymph-node biopsy, and have immediate complete lymph node dissection, do not achieve…
Approaches to Stage II and III Melanoma: Recent Research Context
Melanoma Content Hub
There have been many changes in the treatment landscape of stage II and stage III melanoma over the past decade. This article takes a look at the benefits…
BRAF-Mutated Metastatic Melanoma: Recent Research Context
Melanoma Content Hub
Determining which patients are most likely to benefit from BRAF-targeted therapies was the topic of a recent review by Anna C. Pavlick, DO, MBA, of New York University…
BRAF-Mutated Metastatic Melanoma: Recent Research Context
Melanoma Content Hub
Determining which patients are most likely to benefit from BRAF-targeted therapies was the topic of a recent review in ASCO Educational Book by Anna C. Pavlick, DO, MBA,…
Immune Combo Active in Untreated Melanoma
Melanoma Content Hub
A preliminary clinical study looking at previously untreated metastatic melanoma showed promising results when treating with the combination of an IL-2 signaling agonist and nivolumab. Primary trial objectives…
Long-Term QOL for Melanoma Patients on Immunotherapy
Melanoma Content Hub
Early data from the phase III CheckMate 067 trial, reported in September 2017, showed that patients with advanced melanoma treated with nivolumab, with or without ipilimumab, maintained their quality…
Mohs Tied to Better OS in Early Invasive Melanoma
Melanoma Content Hub
A retrospective study’s multivariate analysis suggests that in the treatment of early invasive melanoma, the use of Mohs micrographic surgery is associated with better outcomes when compared with…
Immunotherapy Combo Fails Melanoma Test
Melanoma Content Hub
Despite an abundance of preclinical evidence supporting the treatment strategy of combining an IDO1 inhibitor with anti-PD-1/PD-L1 immunotherapy, the results of a recent clinical trial were unable to confirm…
Genetic Mutation Predicts Responses to Immunotherapy in Melanoma
Melanoma Content Hub
With the growth of immunotherapies in recent years as an effective melanoma treatment option, there are still patients who do not respond well to immunotherapies. Hildur Helgadottir, MD,…