Andreas Hochhaus, MD, Jena University Hospital, Jena, Germany; Bee Kim Tan, BPharm, MSc, PhD, Taylor’s University, Selangor, Malaysia; and Mr Johan de Munter, a nurse specialist from University Hospital Ghent, Ghent, Belgium, use case studies to discuss management of Ph+ CML as part of a multidisciplinary team. The panelists discuss response-based dosing, assessing side effects, and when to switch drugs, emphasizing the important role cancer nurses and patients should play in managing treatment.