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Immunotherapy Combo Fails Melanoma Test


Despite an abundance of preclinical evidence supporting the treatment strategy of combining an IDO1 inhibitor with anti-PD-1/PD-L1 immunotherapy, the results of a recent clinical trial were unable to confirm the benefit. Adding a second immunotherapeutic agent to a PD-1 inhibitor failed to slow disease progression or improve survival in patients with unresectable or metastatic melanoma.

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