William B. Evans III, MD, Norton Gastroenterology Consultants, Louisville, Kentucky, discusses the most up-to-date guidelines for the diagnosis and management of gastroesophageal reflux disease (GERD) and screening guidelines for Barrett’s esophagus. Dr Evans also discusses GERD complications and the indications for endoscopic evaluation. Notably, a consistent plan for treatment and diagnosis does not always exist between the GI specialist and the primary care provider.