In a phase III, randomized, open-labeled, noninferiority study that compared clinical cure of ventilator-associated pneumonia with doripenem IV with two different does of imipenem IV, length of stay and time on mechanical ventilation were significantly shorter with doripenem compared with imipenem.

References and Resources
Merchant S, Gast C, Nathwani D, et al. Hospital resource utilization with doripenem versus imipenem in the treatment of ventilator-associated pneumonia. Clinical Therapeutics. April 2008;30:717-733.

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