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Balloon dilation as effective as lithotripsy for removal of large bile duct stones

Reuters Health • The Doctor's Channel Daily Newscast

NEW YORK (Reuters Health) – Following endoscopic sphincterotomy, large bile duct stones can be managed as successfully with large balloon dilation as with traditional mechanical lithotripsy, and with fewer complications, according to a report from Greece in The American Journal of Gastroenterology published online November 2.

Dr. Nikos Viazis, with Evangelismos Hospital, Athens, and colleagues note that 90% of bile duct stones can be removed with standard endoscopic maneuvers after endoscopic sphincterotomy, but large stones are a challenge. Large balloon dilation has become an alternative to mechanical lithotripsy, but the two approaches have never been compared head-to-head.

To remedy that, the researchers randomized 90 patients with bile duct stones 12-20 mm to management by large balloon dilation (LBD) or mechanical lithotripsy (ML) following endoscopic sphincterotomy (EST).

“Complete bile duct stone removal was accomplished in 44 out of 45 patients randomized in EST-LBD (97.7 % ) and in 41 out of 45 patients randomized in EST-ML (91.1 %),” the team reports. The difference was not statistically significant (p=0.36).

On follow-up ERCP, complications were noted in two patients who underwent large balloon dilation (4.4%) and in nine patients managed by mechanical lithotripsy (20.0%).

Dr. Viazis and colleagues conclude, “EST-LBD should be the preferred treatment for the endoscopic removal of common bile duct stones with a diameter greater than 12 mm and up to 20 mm.”


Large Balloon Dilation vs. Mechanical Lithotripsy for the Management of Large Bile Duct Stones: A Prospective Randomized Study

Am J Gastroenterol 2010;