Join us for our Abstract Highlights - AACE 2011 Conference - Long Term Effects of Bisphosphonate Drug Holidays. Participants in the 2011 AACE annual meeting discussed a report on the long term effects of bisphosphonate drug holidays. The study authors noted that their study was not powered to assess the risk of fractures during drug holidays, but they concluded that neither the type of bisphosphonate nor the duration of drug holiday significantly affected bone mineral density.