Isaac Kohane, MD chair of Biomedical Informatics at Harvard Medical School, discusses the impact of AI on infectious diseases. He highlights how AI tools, like ChatGPT, are not only aiding doctors but also empowering patients to self-diagnose. Dr. Kohane emphasizes the potential for AI to collect comprehensive patient histories, improving diagnosis accuracy and speed. He also stresses the importance of gathering diverse global data to ensure equitable healthcare advancements, particularly for diseases like malaria and tuberculosis. Public participation is crucial to enhance AI’s effectiveness and fairness across various populations.