The results of a phase II, multicenter trial that included 25 adult patients with newly diagnosed disease reported that patients maintained a complete response to treatment with high-dose methotrexate alone for a primary central nervous system lymphoma.

References and Resources
Gerstner E, et al. Long-term outcome in PCNSL patients treated with high-dose methotrexate and deferred radiation. Neurology 2008; 70: 401-402.

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