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Early Goal Directed Therapy in the Treatment of Sepsis

Study Synopsis

Nathanial Marchetti, DO, Assistant Professor of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University School of Medicine, discusses a clinical study involving early goal directed therapy in the treatment of sepsis.

References and Resources
Rivers E, Nguyen B, Havstad Suzanne, Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock. Nov 2001;Volume 345:1368-1377.
Click Here to read the study Dr. Marchetti discusses.

Neurath M, New therapies for sepsis: focus on the interleukin (IL)12 family member IL27. Annals of the Rheumatic Diseases, 2007;66.
Click Here to read abstract.

ESMON C, Is APC activation of endothelial cell PAR1 important in severe sepsis?: No. Journal of Thrombosis and Hemostasis, 2005; 3(9):1910–1911.
Click Here to read abstract.

Al-Abed Y, Dabideen D, Aljabari B, et al., SO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis. J. Biol. Chem., 2005; Vol. 280:44, 36541-36544.
Click Here to read article.