Michaela Liedtke, MD, Associate Professor at Stanford University Medical Center in Palo Alto, CA, discusses CAR T-cell therapy for patients with multiple myeloma. She also discusses clinical data and the current indication CAR T-cell therapies. Finally, Dr Liedtke discusses toxicities associated with CAR T-cell therapy. She also discusses how next-generation CAR T-cell therapies have been designed to overcome resistance.