Rafael Fonseca, MD, discusses the evolving landscape of multiple myeloma treatment. While traditionally deemed incurable, Dr. Fonseca highlights a growing fraction of patients achieving sustained, durable, and potentially lifelong control through frontline treatments. He explains the varying life expectancies among patients, some requiring multiple lines of therapy, and others living with detectable myeloma. Emphasizing optimism, Dr. Fonseca shares his belief in curable cases and his commitment to positioning new patients for the best possible outcomes, aiming for a future where multiple myeloma can be considered curable.