Martin Lee, director, Project CBD, talks about the JAMA article that highlights the 25 percent decrease in overdose deaths from opiates in states where medical marijuana is legal. According to Lee, cannabis effectively potentiates other compounds, so that individuals who are taking opiates need less of the drug to have the same pain-killing effect. Due to its synergistic interaction with the painkilling opiates, cannabis is useful in lowering the risk of opiate overdose. Resources & References