Michael Levy, MD, PhD, associate professor at Harvard Medical School and research director in the Division of Neuroimmunology at Massachusetts General Hospital, discusses research on neuromyelitis optica, MOG antibody disease, and familial transverse myelitis. Dr Levy describes the immunological differences and treatment options for these conditions. The monophasic form of transverse myelitis is very rare, occurring in about 1 in 500,000.