David Heber, MD, Professor of Medicine, Director, UCLA Center for Human Nutrition, discusses diabesity, obesity with diabetes, and reminds doctors why we need to screen patients first for obesity and then metabolic syndrome. A 5% decrease in weight leads to a 58% reduction in the incidence of diabetes. Obesity swallows 10% of the national health care budget.

Reading:
Bailey CJ. New therapies for diabesity. Curr Diab Rep. 2009 Oct;9(5):360-7.
Hosek J, Bartos M. [Gene expression changes during insulin resistance and “diabesity” in insulin-sensitive tissues and possibilities of their regulation] Cas Lek Cesk. 2008;147(7):360-6. Review. Czech.
Krajewska M, Banares S, Zhang EE, Huang X, Scadeng M, Jhala US, Feng GS, Krajewski S. Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase. Am J Pathol. 2008 May;172(5):1312-24. Epub 2008 Apr 10.

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