Merit E. Cudkowicz, MD, MSc, chief of the Department of Neurology and director of the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, discusses the importance of accelerating diagnoses for ALS and the new advances in therapeutic development to treat this disease. It takes approximately 1 year from initial symptoms to diagnosis of ALS. Neurologists typically make the diagnosis. BIIB067, an investigational gene therapy, has been recently studied for a hereditary type of ALS with promising results. Dr Cudkowicz also notes that several other drugs are under investigation to be repurposed to treat patients with ALS.