Obi Umeh, MD, MSc, VP, Franchise Global Program Leader at Takeda, discusses interim results from a study investigating mezagitamab for the treatment of patients with IgA nephropathy. This…
Dana Rizk, MD, professor of medicine at the University of Alabama at Birmingham, discusses the approval of Fabhalta (iptacopan) for adults with IgA nephropathy. Iptacopan, a Factor B…
David Simel, MD, and William Kim, MD, explore renal cell carcinoma in this JAMA Clinical Review podcast. They discuss key insights from the 2019 Nobel Prize research on…
Advances in non-small cell lung cancer (NSCLC) treatment have transformed care from a one-size-fits-all approach in the 1990s to highly personalized regimens today. Treatment now considers actionable mutations…
Faith Davies, MD, shares insights from the IMS 2024 session on high-risk disease, highlighting the debut of a unified high-risk definition. This new framework incorporates 17p deletions, mutations,…
Muneeb Shah MD, and Luke Maxfield, MD, break down the essentials of skin cancer, explaining the causes, symptoms, and treatments of basal cell carcinoma, squamous cell carcinoma, and…
The dialogue between Venugopal, MD, and Nabhan, MD, delves into unresolved challenges in treating chronic myeloid leukemia (CML). Venugopal emphasizes the need for targeted therapies in CML blast…
Pompe disease is a progressive, life-threatening genetic neuromuscular disorder. Late-onset Pompe disease (LOPD), affecting individuals over one year old, leads to trunk and proximal muscle weakness, often impacting…
Beth A. Vogt, MD discusses Post-infectious Glomerulonephritis (GN), often following strep infections, affects children aged 5-15. Symptoms typically emerge 7-14 days post-infection and include cola-colored urine, edema, hypertension,…
Ulcerative colitis is a chronic inflammatory bowel disease that affects the colon and rectum, causing symptoms like abdominal pain, bloody diarrhea, rectal urgency, and fatigue. Sanjay Murthy, MD,…
The FDA has approved MTAV, a groundbreaking treatment for melanoma, a potentially deadly skin cancer. Known as tumor-infiltrating lymphocyte (TIL) therapy, this innovative approach uses a patient’s own…
Polycystic Kidney Disease (PKD) is a genetic condition causing cysts to grow in the kidneys, potentially leading to kidney failure. Symptoms may include back pain, blood in urine,…