Medicine (Baltimore)
Venetoclax combined with azacitidine in elderly AML
Yu Z, Li S, Pei R, Lu Y, Wang Y, Yuan J
In this study, the authors retrospectively analyzed 90 treatment-naive elderly patients with AML receiving venetoclax + azacitadine, including 47 patients receiving 14 days of venetoclax and 43 patients receiving 28 days of venetoclax. A 14-day venetoclax + azacitadine regimen had comparable antileukemic efficacy versus the 28-day protocol while mitigating myelosuppressive sequelae. This approach may optimize tolerability in certain frail elderly patients.
Previous Article
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