In a recent study, fluoxetine (Prozac) decreased progression of relapsing-remitting MS in a small placebo-controlled study, but the effect lasted only a few months.

References and Resources
Mostert J, et al. Effects of fluoxetine on disease activity in relapsing multiple sclerosis: A double-blind, placebo-controlled, exploratory study. Journal of Neurology, Neurosurgery, and Psychiatry. 2008 May;(2):35-37.

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