Janna Andrews, MD, discusses the clinical threshold for when a physician should consider preforming a biopsy after preforming a PSA exam to screen for prostate cancer. She also  reviews the recent controversy to lower the threshold, as some physicians believe decreasing the cut-off could potentially increase the sensitivity of the exam. References: Bio for Janna Andrews, MD Faculty and Financial Disclosures: Dr. Andrews has no relevant financial disclosures.