Jonathan Sears, MD, Associate Professor of Ophthalmology, Cole Eye Institute, Cleveland Clinic, discusses reversing phase 1 and 2 of ROP by turning down oxygen levels to encourage retinal growth.

Recent data and clinical trials have demonstrated that by turning down oxygen levels in premature infants to mimic the level of oxygen delivery to the retina in utero, phase 1 and 2 ROP can be reversed.

References and Resources:
Ahmed AS, Muslima H, Anwar KS, Khan NZ, Chowdhury MA, Saha SK, Darmstadt GL. Retinopathy of prematurity in Bangladeshi neonates. J Trop Pediatr. 2008 Oct;54(5):333-9. Epub 2008 May 25.
Askie LM, Henderson-Smart DJ. Gradual versus abrupt discontinuation of oxygen in preterm or low birth weight infants. Cochrane Database Syst Rev. 2001;(4):CD001075. Review.

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