In a multi-speaker session on medical dermatology, Dawn L. Sammons, DO; Joslyn R. Sciacca Kirby, MD, MS; Boni E. Elewski, MD; and David M. Pariser, MD, provide clinical and therapeutic pearls. Dr Sammons, Oakview Dermatology, Athens, Ohio, discussed painless photodynamic therapy. Dr Kirby, Penn State Health Dermatology, Hershey, Pennsylvania, discussed infliximab for hidradenitis suppurativa. Dr Elewski, University of Alabama at Birmingham discussed oral minoxidil for patients with alopecia. Dr Pariser, Pariser Dermatology Specialists, Norfolk, Virginia, stressed the importance of not using veterinary lidocaine, even considering the lidocaine shortage.