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Infertility and Polycystic Ovarian Syndrome

Treatment with clomid and metformin

Dr. Lubna Pal, MD, is a Director of the Reproductive Aging and Bone Health Program at Yale Reproductive Endocrinology, specializing in the areas of infertility, reproductive aging and menopause, low bone mineral density (osteopenia and osteoporosis), and reproductive endocrinology. She discusses infertility in women with PCOS and the best treatment options, focusing on clomid and metformin.

Summary
Women with PCOS have trouble ovulating. Clomid can induce ovulation and achieve pregnancy better than metformin, however metformin can help maintain a healthy mother and baby who are at risk of diabetes related to their PCOS. A combination of these treatments will be more likely to produce a healthy pregnancy.

References and Resources
Karimzadeh MA, Javedani M. An assessment of lifestyle modification versus medical treatment with clomiphene citrate, metformin, and clomiphene citrate-metformin in patients with polycystic ovary syndrome. Fertil Steril. 2009 May 20.

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