Andrew Blauvelt, MD, MBA, Oregon Medical Research Center, Portland, Oregon, and Nehal Mehta, MD, George Washington University, Washington DC, discuss psoriasis. Dr Blauvelt discusses how to target genes for psoriasis, 12-week treatment, and IL-17 and IL-23 inhibitors. Dr Mehta focused on the discussion of cardiometabolic disease in patients with psoriasis.