Stuart Mazzone, PhD, University of Melbourne, Victoria, Australia; Peter Kardos, MD, Red Cross Maingau Hospital, Frankfurt am Main, Germany; and Alyn Morice, MD, University of Hull, Hull, UK, discuss different aspects of chronic cough, including the mechanisms of cough, what is chronic cough, and harm and debilitation associated with chronic cough. Patients with chronic cough also share their own experiences.