Jennifer Crombie, MD, Dana-Farber Cancer Institute, Boston, Massachusetts, discusses results from a real-world study of lisocabtagene maraleucel in patients with relapsed/refractory large B-cell lymphoma. Similar to published findings…
Tanya Siddiqi, MD, medical director of lymphoma, City of Hope, Orange County, California, discusses the primary analysis of the TRANSCEND CLL 004 trial. This phase 1/2, single-arm, multicenter…
Omar Krad, MD, shares his practical approach to cataract surgery in patients with wet macular degeneration. This case involves a diabetic, hyperopic patient with vision limited to counting…
Charles C. Wykoff, MD, highlights both the success and the limitations of current treatments for wet AMD. While anti-VEGF therapies are effective at controlling bleeding and leakage in…
Pompe disease is a rare, life-threatening genetic disorder caused by GAA enzyme deficiency, leading to glycogen buildup and muscle cell destruction. It presents on a spectrum, from infantile-onset…
Board-certified nephrologist Blake Shusterman, MD, debunks common kidney health myths. Urinating normally doesn’t guarantee healthy kidneys, and nocturnal urination is often due to aging or other conditions, not…
Ulcerative colitis can cause persistent digestive issues that disrupt daily life. Symptoms may include diarrhea, frequent and urgent bowel movements, blood or pus in stool, severe cramps, nausea,…
Melanoma immunotherapy has a critical limitation: 40 to 60% of patients don’t respond. Arielle Elkrief, MD, discusses an innovative approach targeting the gut microbiome. By using fecal microbiota…
Rheumatoid arthritis isn’t just about joint pain—it can affect multiple organs, leading to complications like heart disease, lung fibrosis, eye conditions, skin vasculitis, and nervous system issues. Micah…
Mark R. Barakat, MD, founder and director of research, Retina Macula Institute of Arizona, discusses an analysis of the Phase 2/3 PHOTON trial. Dr Barakat explained that pre-dose…
Jimmy Ruiz, MD, reflects on his career journey in North Carolina and the transformative progress in lung cancer treatment. Early in his career, limited tools like chemotherapy presented…
David Simel, MD, and William Kim, MD, explore renal cell carcinoma in this JAMA Clinical Review podcast. They discuss key insights from the 2019 Nobel Prize research on…
