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Provider Statement

This continuing medical education activity is provided by Vindico Medical Education.

Support Statement

This activity is supported by an educational grant from Genentech, Inc.

Target Audience

The intended audience for the activities is emergency medicine physicians, neurologists, emergency medicine residents, nurses, physician assistants, nurse practitioners, and other health care professionals involved in the treatment of patients with AIS.

Learning Objectives

Upon successful completion of this video series, participants should be better able to:

  • Apply evidence-based criteria to the selection of candidates for thrombolytic therapy in AIS.
  • Evaluate FDA labeling, current data, and clinical practice guidelines on the use of tissue plasminogen activator in the extended 3-hour to 4.5-hour post-onset window.
  • Assess recent studies and guidelines on endovascular procedures for AIS.
  • Determine the criteria for the concomitant or preferential use of tissue plasminogen activator in patients with AIS who are being considered for endovascular procedures.
  • Incorporate shared decision making with patients and their families to improve education and assist in reducing delays in treatment and complications.


Andy S. Jagoda, MD, FACEP
Professor and Chair
Department of Emergency Medicine
Icahn School of Medicine at Mount Sinai
New York, NY

Philip B. Gorelick, MD, MPH, FACP
Medical Director
Hauenstein Neuroscience Center
Saint Mary's Health Care
Professor, Translational Science and Molecular Medicine
Michigan State University
Grand Rapids, MI

Physician Information


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™, 0.25 credits for each video. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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Nurse Information

This activity is provided by Vindico Medical Education.

This continuing education activity is supported by an educational grant from Genentech, Inc.

There is no non-commercial support for this activity.

Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.


Vindico Medical Education, LLC is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Credit Designation

Vindico Medical Education will provide 0.50 contact hours for nurses, 0.25 contact hours for each video.
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Nurse Practitioner Information

This activity is approved for 0.50 contact hour(s) of continuing education by the American Association of Nurse Practitioners. Activity ID 16092352. This activity was planned in accordance with AANP CE Standards and Policies.

Physician Assistant Information

This program has been reviewed and is approved for a maximum of 0.50 AAPA Category 1 CME credits by the PA Review Panel. Approval is valid for one year from the issue date of 11/10/2016. Participants may submit the posttest at any time during that period.

This program was planned in accordance with AAPA's CME Standards for Enduring Material Programs and for Commercial Support of Enduring Material Programs.

This enduring material is approved for 1 year from the date of original release, November 10th, 2016 to November 9th, 2017.
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How To Participate in this Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the pretest questions, view the videos, complete the CME posttest, and complete the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering correctly 2 out of 3 posttest questions for each video. If a satisfactory score on the posttest is achieved, Vindico Medical Education will issue a credit certificate

Steering Committee and Faculty

Philip B. Gorelick, MD, MPH, FACP

Andy S. Jagoda, MD, FACEP

Edward C. Jauch, MD, MS, FAHA

Nurse Planners

Barbara A. Niedz, PhD, RN, CPHQ

Natalie Wilson, MS, RN


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears below.

Planning Committee and Faculty members report the following relationship(s):

Philip B. Gorelick, MD, MPH, FACP

Speakers Bureau: Boehringer Ingelhelm, New Haven Pharmaceutical

Other: Malpractice litigation relating to acute stroke management, including intravenous tPA administration

Andy S. Jagoda, MD, FACEP

Royalty: Elsevier, McGraw-Hill

Consulting Fee: Banyan Biomarkers, Daiichi Sankyo, Janssen, Mallinckrodt, Pfizer

Medical Education Honoraria: Genentech

Executive Committee: Brain Attack Coalition

Edward C. Jauch, MD, MS, FAHA

Contracted Research: Genentech (Paid to institution), Penumbra

Nurse Planners report the following relationship(s):

Barbara A. Niedz, PhD, RN, CPHQ

No relevant financial relationships to disclose.

Natalie Wilson, MS, RN

No relevant financial relationships to disclose.

External Reviewers reports the following relationship(s):

Todd J. Crocco, MD, FACEP

No relevant financial relationships to disclose.

Linda Giarraputo, PA-C

No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relationship(s):

No relevant financial relationships to disclose

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.


The treatment of acute ischemic stroke (AIS) is time sensitive and requires rapid assessment to provide treatment for minimizing brain damage. However, current evidence indicates that clinicians involved in the management of patients with AIS report several critical gaps in knowledge and performance related to evidence-based stroke care. In this activity, leading neurologists and emergency medicine physicians will discuss recent criteria and guidelines for using thrombolytic therapy in AIS patients; current data on the use of tissue plasminogen activator, including patients being considered for endovascular procedures; as well as recent guidelines on endovascular procedures for AIS.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2016 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

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