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Sick of the Needle? Nanoparticle Technology Regulates Glucose for Up to 10 Days

A new study in ACS Nano investigates the potential for an artificial “closed-loop” system to mimic pancreas activity and release insulin in response to glucose level changes. Researchers developed a “glucose-mediated release strategy for the self-regulated delivery of insulin using an injectable and acid-degradable polymeric network.” The nanocomposite-based porous architecture can be dissociated and can subsequently release insulin in response to glucose concentrations. In vivo studies demonstrated improved glucose control in type 1 diabetic mice with a single injection that stabilized blood glucose levels in the normoglycemic state (<200 mg/dL) for up to 10 days.

Read it in ACS Nano.