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Candidates and Criteria for IV Thrombolysis in Acute Ischemic Stroke
Course List
  • CME Front Matter

Downloadable Education Resources

Provider Statement

This continuing medical education activity is provided by Vindico Medical Education

Support Statement

This activity is supported by an educational grant from Genentech, Inc.

Target Audience

The intended audience for the activity is neurologists, emergency medicine physicians, and other health care professionals involved in the treatment of patients with acute ischemic stroke.

Learning Objectives

Upon successful completion of this video series, participants should be better able to:

  • Implement practices that improve the door-to-needle time in patients presenting with symptoms of acute ischemic stroke.

  • Apply the evidence, results from clinical studies, and best practices when determining the safety, effective use, and timing of thrombolysis in acute ischemic stroke.

  • Determine when endovascular procedures, with or without initial intravenous thrombolysis, would be beneficial in patients experiencing acute ischemic stroke.

  • Examine established systems of coordinated stroke care and their impact on patient outcomes.

Activity Chair

Edward C. Jauch, MD, MS, FAHA, FACEP
Division Director and Professor
Department of Medicine, Division of Emergency Medicine
Professor, Department of Neurosciences
Associate Vice Chair, Research, Department of Medicine
Medical University of South Carolina
Charleston, SC


Philip B. Gorelick, MD
Medical Director, Hauenstein Neuroscience Center
Mercy Health at Saint Mary's
Professor, Translational Science and Molecular Medicine
Michigan State University College of Human Medicine
Grand Rapids, MI

Kama Z. Guluma, MD
Clinical Professor
Department of Emergency Medicine
University of California San Diego Health System
San Diego, CA

Andy S. Jagoda, MD
Professor and Chair in the Department of Emergency Medicine
Mount Sinai School of Medicine
New York, NY


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™, 0.25 credits per video. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, April 17, 2015 to April 16, 2016.

How To Participate in this Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the pretest questions, read the articles, complete the CME posttest, and complete and return the registration form and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering correctly 3 out of 4 posttest questions for each video. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

Planning Committee and Faculty

Edward C. Jauch, MD, MS, FAHA, FACEP
Philip B. Gorelick, MD
Kama Z. Guluma, MD
Andy S. Jagoda, MD


Todd J. Crocco, MD


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears below.

  • Planning Committee and Faculty members report the following relationship(s):

    • Philip B. Gorelick, MD, MPH
      • Consulting Fee: Lundbeck

    • Kama Guluma, MD
      • No relevant financial relationships to disclose

    • Andy S. Jagoda, MD
      • Consulting Fee: Banyan Biomarkers, Janssen, Pfizer, Teva
      • Executive Board: FERNE

    • Edward C. Jauch, MD MS
      • Contracted Research: Covidien, Genentech, Penumbra, Stryker

  • Reviewer reports the following relationship(s):

    • Todd J. Crocco, MD
      • No relevant financial relationships to disclose

  • Vindico Medical Education staff report the following relationship(s):
    • No relevant financial relationships to disclose

  • Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.


Stroke management is time sensitive. Treatment options for acute ischemic stroke (AIS) have advanced from simple supportive care to complex decisions involving intravenous (IV) thrombolysis and endovascular procedures. The safety and efficacy of IV and intra-arterial (IA) thrombolysis have been debated and tested for decades in numerous trials. Benefits of clot retrieval devices have been questioned. How can these treatments and procedures be safely used? Who will benefit most from them? What are the potential risks? In this activity, leading emergency physicians and neurologists discuss current stroke management and how results from recent trials may change clinical practice by providing long-awaited answers to persistent, age-old questions. Faculty members provide evidence-based insight on how to reduce door-to-needle time and improve patient outcomes by working within established stroke systems of care, while considering the safety and efficacy of various therapeutic options available for the treatment of AIS.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2015 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.


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