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Genetic Mutation Sets Off Drug Race

An article in The New York Times reports that a discovery of two women with a rare genetic mutation leading to exceptionally small low-density lipoprotein (LDL) levels has “set off one of the greatest medical chases ever.” The mutation left the women with LDL levels below 20. Now, pharmaceutical companies are competing to “test and win approval for a drug that mimics the effects of the mutation.” In clinical research, the drug is injected once or twice a month and has been shown to reduce LDL levels from well over 100 to levels to as far as below 40.

Read it in The New York Times.