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Drug That Caused Harmful Side Effects in 2006 Returns to Testing Phase

According to Reuters, an experimental drug that infamously caused horrific side effects almost a decade ago, from a ballooned head on one patient, to lost fingertips and toes on another, is back in tests for rheumatoid arthritis. Scientists have since learned to study the interaction of the drug with human cells within a test tube in order to calculate a safe starting dose, and the drug (now owned by TheraMAB LLC) is showing some promise when administered at a fraction of the original dose. This does not mean the drug will eventually be brought to market, it may fail in later-stage studies or may prove uncompetitive against existing treatments. Small Phase I tests have shown signs of reducing arthritis symptoms, and may be tested against lupus and psoriasis at a later time.

Read the article published by Reuters.