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Cancer Genome Atlas Finds Genetic Similarity Between Different Tumor Types

The Los Angeles Times reports on a study in Nature Genetics that has identified common genetic patterns underlaying several different types of tumors. The Cancer Genome Atlas, or TCGA, “has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels.” They found striking similarities in the genetic codes of tumors originating in different organs. Some examples include the TP53 mutations that cause ovarian, endometrial, and basal-like breast carcinomas, as well as ERBB2-HER2 mutations which are amplified in subsets of glioblastoma, gastric, serious endometrial, bladder and lung cancers. The findings offer important treatment implications for many different types of cancer.

Read it in the Los Angeles Times.

Read the study in Nature Genetics.