Emmanouil Nikolousis, MD, PhD, consultant hematologist at Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, along with a clinical nurse specialist and a patient with AML, discuss the current treatment armamentarium for AML. Treatment decision-making occurs in a multidisciplinary fashion that is reassuring to patients. Long-term side effects of AML treatment may include secondary cancers, such as myelodysplastic syndrome. While receiving treatment, it is important to monitor general well-being and blood counts.