A 68-year-old male presented with a 4-day history of a worsening, painful rash on his lower abdomen. He had been in the hospital in the last 10 days for a partial colon resection for colon cancer — with an abdominal incision higher up on the abdomen. The inflamed nodule is not part of surgical incision but is located within the surgical field that was shaved. He has been treated with 500mg of cephalexin four times a day for the last four days, but the condition has worsened.
A bacterial culture confirmed the clinical suspicion of methicillin-resistant Staphylococcus aureus, which responded to an incision and drainage and a changing of the antibiotics. While an incision and drainage is usually sufficient in uncomplicated cases, the recent surgery probably contributed to the introduction of the Staph infection by introducing micronicks into the skin. The rapid spread and presence of pain reduces the likelihood of metastatic cancer. Treatment should include the nares for the presumed site of the Staph carrier. Oral corticosteroids would not be indicated with this presentation.