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Roche says Avastin slows glioblastoma growth

ZURICH (Reuters) – Swiss drugmaker Roche Holding said a new study of cancer drug Avastin (bevacizumab) showed it significantly extended progression-free survival of people with glioblastoma.

The Phase III AVAglio study met one of its main targets of improving progression-free survival, Roche said in a statement on Friday.

“This study showed that people with glioblastoma, a particularly devastating and aggressive cancer without many treatment options, lived significantly longer without their disease worsening when Avastin was added to radiation and temozolomide chemotherapy,” Roche said.

Data for final overall survival, the study’s other main endpoint, is expected in 2013, the Basel-based company said.

Roche also said that no new safety findings were observed in the study and that adverse events were consistent with those seen in previous trials of Avastin across tumor types for approved indications.