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Psoriasis Severity Linked to Increased Risk of Serious Comorbid Diseases

A new study in JAMA Dermatology finds that “the burdens of overall medical comorbidity and of specific comorbid diseases increase with increasing disease severity among patients with psoriasis.” Although it is “conventionally considered a disease limited to the skin and joints, increasing evidence suggests that psoriasis has far-reaching systemic effects,” and this study demonstrated a link between the common skin condition and several far-ranging medical problems: myocardial infarction, peripheral vascular disease, diabetes, diabetes-associated systemic complications (including nephropathy, retinopathy, neuropathy, and vasculopathy), hyperglycemiarenal diseasechronic obstructive pulmonary disease, peptic ulcer disease, and autoimmune rheumatologic diseases beyond psoriatic arthritis. The study’s sample consisted of 4,500 mild, 3,000 moderate, and 1,000 severe psoriasis cases.

Read the study in JAMA Dermatology.