Russell K. Portenoy, MD, Chairman, Department of Pain Medicine & Palliative Care at Beth Israel Medical Center in New York, discusses important exceptions to the general rules guiding opioid rotation. One involves a significant downward adjustment of the equianalgesic dose when switching from any other opioid to methadone. The second involves switching to the fentanyl patch, in which case the initial dose should be the calculated equianalgesic dose.

This content was developed with Russell Portenoy, MD.

Russell Portenoy, MD has indicated the following financial disclosures during the past 12 months:

  • Advisor/speaker
  • Arsenal Medical Inc.
  • Grupo Ferrer
  • Xenon

Departmental educational/research grants

  • Ameritox
  • Archimedes Pharmaceuticals
  • Boston Scientific
  • Covidien Mallinckrodt Inc.
  • Endo Pharmaceuticals
  • Forest Labs
  • K-Pax Pharmaceuticals
  • Meda Pharmaceuticals
  • Medtronics
  • Otsuka Pharma
  • ProStrakan
  • Purdue Pharma
  • Salix
  • St. Jude Medical