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New Research May Lead to HIV Treatment

The Los Angeles Times reports that “Scientists say they have discovered a key process by which the AIDS virus kills key immune cells: It triggers a preprogrammed self-destruct sequence within the cell that is intended to alert fellow immune cells of a crisis.” In addition to the discovery of this process, researchers also identified an existing drug that may stop it. The researchers found that the virus is “detected by interferon-gamma-inducible protein 16, which in turn activated the cell’s trigger for pyroptosis, an enzyme called caspase 1.” They then “tested different caspase 1 inhibiting compounds on infected tissues and found that some were as effective in preventing the depletion of CD4 T cells as viral inhibiting drugs.”

Read the article published by the Los Angeles Times.