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Muscle Soreness Begins With These Important Chemicals

A new study in Experimental Physiology helps elucidate why exactly we experience muscle soreness and fatigue when exercising and whether we have an upper limit, The New York Times’ Well blog reports. Researchers injected a combination of lactate, certain acids, and adenosine triphosphate into the thumbs of participants based on previous findings that showed that this combination causes nerve cells to react in a particular way. With increasing amounts of the injections, subjects reported increased amounts of fatigue in their thumbs, similar to what they would experience after exercise. Experts explain that the “feeling of fatigue in our muscles during exercise ‘probably begins’ when these substances start to build up” and that they are a warning sign that complete fatigue will soon occur.

Read it in The New York Times’ Well blog.

Read the study in Experimental Physiology.