ADT typically instituted early and has been shown to delay the onset of complication of those with metastatic disease.
However, it has limitations, and is not curative and is associated with the emergence of resistance and progression of disease.
Current and emerging treatment modalities for metastatic castration-resistant prostate cancer.
Bracarda S, Logothetis C, Sternberg CN, Oudard S.
BJU Int. 2011 Apr;107 Suppl 2:13-20.