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Does This Diabetes Drug Increase Life Span?

BBC News reports that metformin may “mimic the effects of extreme calorie restriction” to provide anti-aging and life-extending effects. The pill demonstrated its anti-aging and life-extending effects on male mice, according to a new study. Researchers say the longevity-increasing effect of metformin is unknown in humans. Metformin has shown life span increasing effects on worms in previous studies, but “studies in flies and mammals have given conflicting evidence.” Small doses on lab mice resulted in a 5% lifespan increase, but large doses were “toxic and reduced the lifespan of mice.” Researchers conclude that more study is needed to find out if metformin provides any anti-aging or life-extending effects for humans.

Read it in BBC News.

Read it in Nature Communications.