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Can We Use Smartphones to Sequence DNA and Detect Mutations?

Molecular analysis of biological samples is typically outsourced to well-equipped (and cost-intensive) laboratories. However, there are times when sample diagnosis and DNA sequencing is needed quickly, needed in a remote location, or both. For this reason, Professor Mats Nilsson of Stockholm Universitet, Uppsala Universitet, and SciLifelab has led research on creating a smartphone compatible device for rapid, cost-effective molecular analysis.

The 3d-printed smartphone attachment uses a specialized lens and two LED lights to perform its microscopy. One of the first use-cases that Prof. Nilsson envisions for the technology is identifying antibiotic resistance in tuberculosis in developing countries. When the device becomes widely available, it’s estimated that it will cost less than $500.

Click here to read the paper published in the journal Nature Communications.