Bladder sparing trimodal therapy (TMT) and cystectomy were studied in a retrospective propensity score analysis. The study included 112 patients with a mean follow-up time of 4.5 years. Both therapies had similar overall and disease-specific survival rates and the mortality rates differed only slightly. Patients who underwent TMT did have a higher frequency of recurrence and 10.7% required salvage cystectomy. The researchers concluded that TMT therapy could be a viable treatment option for a select group of patients, though the patients would need to be properly monitored by urologic oncologists due to the possible need for salvage cystectomy.
Blevins Primeau, A.S. Bladder sparing therapy outcomes similar to cystectomy in bladder cancer. Cancer Therapy Advisor website. http://www.cancertherapyadvisor.com/renal-cell-carcinoma/bladder-cancer-cystectomy-sparing-therapy-outcomes-treatment/article/651002/. April 17, 2017. Accessed April 20, 2017.