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A New Drug for Chorea?

A new drug called Austedo, has been approved by the FDA for the treatment of involuntary movements associated with chorea. Austedo is a small molecule drug designed to regulate neuronal levels of dopamine and was successful in suppression of movements associated with chorea in Phase III clinical trials. However, the drug does offer unwanted side effects that include an increased risk of depression and suicidal thoughts, which could limit its use.