The Doctor's Channel - Diabetes & Endocrinology

Partnership to Fight Chronic Disease: A Young Girl Shares Her Story

2008-07-11T15:09:37-04:00

Partnership to Fight Chronic Disease is a national coalition of patients, providers, community organizations, business and labor groups and health policy experts, committed to raising awareness of policies and practices that save lives and reduce health costs through more effective prevention and management of chronic disease.

Sarah Yourman, an 18-year-old who suffers from cystic fibrosis, diabetes and Crohn’s disease is a compelling speaker and advocate. In her daily life, she must balance school, sports and other typical teenage activities with lengthy lung treatments and multiple medications. She credits quality healthcare, disease management and treatment innovations for what she still believes is a relatively normal teenage life.

For more information visit:
Partnership to Fight Chronic Disease

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VEGF Inhibitor Found Clinically Helpful for Metastatic Thyroid Cancer

2008-07-08T17:58:05-04:00

According to a small multi-center, phase II trial reported in NEJM, an investigational targeted drug for some patients with metastatic thyroid cancer can induce partial responses.

References and Resources
Sherman S, Wirth W, Droz J, et al. Motesanib diphosphate in progressive differentiated thyroid cancer. N Engl J Med. 2008; 359: 31-42.

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Hormone Therapy and the Risk of Cardiovascular Disease

2008-05-15T16:13:25-04:00

Pamela B. Morris, MD, Director, Preventive Cardiology, Co-Director, Women’s Heart Care, Medical University of South Carolina, discusses hormone therapy and the risk of cardiovascular disease in women.

References and Resources
McGarry KA. Menopause: introduction. Med Health R I. 2008 Mar;91(3):72.

Billeci AM, Paciaroni M, Caso V, Agnelli G. Hormone replacement therapy and stroke. Curr Vasc Pharmacol. 2008 Apr;6(2):112-23.

Rees M, Stevenson J; British Menopause Society Council.
Primary prevention of coronary heart disease in women. Menopause Int. 2008 Mar;14(1):40-5.

For more information on this physician visit:
Pamela B. Morris, M.D.

Views: 2346
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Blood Glucose Monitoring in the Peri-Operative Period in Heart Surgery

2008-05-13T18:32:44-04:00

John Kratz, MD, Professor, Department of Surgery, Medical University of South Carolina, discusses blood glucose monitoring in the peri-operative period in heart surgery.

References and Resources
Hovorka R, Kremen J, Blaha J, et al. Blood glucose control by a model predictive control algorithm with variable sampling rate versus a routine glucose management protocol in cardiac surgery patients: a randomized controlled trial. J Clin Endocrinol Metab. 2007 Aug;92(8):2960-4.

Kersten JR, Warltier DC, Pagel PS. Aggressive control of intraoperative blood glucose concentration: a shifting paradigm? Anesthesiology. 2005 Oct;103(4):677-8.

Pennell L, Smith-Snyder CM, Hudson LR, Hamar GB, Westerfield J. Practice changes in glycemic management and outcomes in coronary artery bypass surgery patients. J Cardiovasc Nurs. 2005 Jan-Feb;20(1):26-34.

For more information on this physician visit:
John M. Kratz, M.D.

Views: 762
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Role of the Extracellular Matrix in Wound Healing

2008-05-12T10:15:26-04:00

James B. McGuire, DPM, PT, Director, Leonard Abrams Center for Advanced Wound Healing of the Foot and Ankle Institute, Department of Podiatric Medicine and Orthopedics, Temple University School of Podiatric Medicine, Philadelphia, PA, discusses the role of the extracellular matrix in wound healing.

References and Resources
Muller M, Trocme C, Lardy B, Morel F, Halimi S, Benhamou PY. Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing. Diabet Med. 2008 Apr;25(4):419-26.

Owen CA. Leukocyte cell surface proteinases: Regulation of expression, functions, and mechanisms of surface localization. Int J Biochem Cell Biol. 2008;40(6-7):1246-72.

Rhett JM, Ghatnekar GS, Palatinus JA, O'Quinn M, Yost MJ, Gourdie RG. Novel therapies for scar reduction and regenerative healing of skin wounds. Trends Biotechnol. 2008 Apr;26(4):173-80.

Views: 470
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Association Between GI and GL of Diet, and Risk of Lifestyle-Related Diseases

2008-03-14T09:21:04-04:00

The study provides compelling evidence that diets with a high GI or a high GL will increase the risk of type 2 diabetes and heart disease.

References and Resources
Barclay A, Petocz P, McMillan-Price J, et al. Glycemic index, glycemic load, and chronic disease risk—a meta-analysis of observational studies. American Journal of Clinical Nutrition. 2008. Vol. 87, No. 3:627-637.

Views: 2543
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New Development in Diabetes Research

2008-03-12T13:14:01-04:00

New research shows an experimental model based on transplanting Islets of Langerhan cells onto the anterior chamber of the mouse eye. This may pave the way for radical approaches to diabetes research.

Reference and Resources
Speier S, Nyqvist D, Cabrera O, et al. Non-invasive in vivo imaging of pancreatic islet cell biology. Nature Medicine. 7 March 2008.

Views: 1472
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Recall of Heparin Sodium Injection and Heparin Lock Flush Solution

2008-02-29T16:14:52-05:00

The FDA has issued an update to inform the public that Baxter Healthcare Corporation has extended its recall of multi-dose vials of heparin sodium for injection to also include single-dose vials of heparin sodium for injection.

References and Resources
FDA Public Health Update
Recall of Heparin Sodium Injection and Heparin Lock Flush Solution (Baxter)

Views: 2129
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Evaluation of Adrenal Masses

2007-12-17T15:51:57-05:00

Howard Simon, MD, Director, Newly Invasive and Bariatric Surgery, State University Hospital Syracuse, discusses adrenal masses.

References and Resources
Pacak, K., Eisenhofer, G., Grossman, A., Gavras, I. The Incidentally Discovered Adrenal Mass. NEJM. 2007. 356: 2005-2006.

Karagiannis A, Mikhailidis D, Athyros V, and Harsoulis F. Pheochromocytoma: an update on genetics and management. Endocrine-Related Cancer. 2007. 14 (4) 935-956.

Song, J. H., Chaudhry, F. S., Mayo-Smith, W. W. The Incidental Indeterminate Adrenal Mass on CT (> 10 H) in Patients Without Cancer: Is Further Imaging Necessary? Follow-Up of 321 Consecutive Indeterminate Adrenal Masses. Am. J. Roentgenol. 2007. 189: 1119-1123.

Views: 1808
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Avandias' New Warning

2007-11-27T09:27:43-05:00

This update highlights changes to the prescribing information for Avandia including a new boxed warning about the potential increased risk of myocardial ischemia.

References and Resources
FDA adds a new warning about the risk of myocardial ischemia to the boxed warning for Avandia.

Click Here to view update.

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